Host versus Virus
Exploring the arms race
The history of the human race is fights against infectious diseases particularly caused by virus.
The Ikeda lab investigates at molecular, cellular and individual levels how hosts defend against viruses (particularly retroviruses) using restriction factors (e.g. APOBEC3 family proteins) and how viruses evolve adaptation mechanisms to cope with the virus restrictions.
Another goal of the Ikeda Lab is to translate these fundamental scientific discoveries into novel therapeutics against viruses.